McDonald, Bruce, Prof.



Using dynamic diversity to achieve durable disease resistance in agricultural ecosystems
The influence of genetic drift and selection on quantitative traits in a plant pathogenic fungus
Measuring quantitative virulence in the wheat pathogen Zymoseptoria tritici using high-throughput automated image analysis
Hitchhiking selection is driving intron gain in a pathogenic fungus
Emergence and early evolution of fungicide resistance in North American populations of Zymoseptoria tritici
Comparative analysis of mitochondrial genomes from closely related Rhynchosporium species reveals extensive intron invasion
Can high-risk fungicides be used in mixtures without selecting for fungicide resistance?


The population genetic structure of Rhizoctonia solani AG-3PT from potato in the Colombian Andes
Population structure and pathotype diversity of the wheat blast pathogen Magnaporthe oryzae 25 years after its emergence in Brazil
Population genetic structure of Mycosphaerella graminicola and Quinone Outside Inhibitor (QoI) resistance in the Czech Republic
Population genetic evidence that basidiospores play an important role in the disease cycle of rice-infecting populations of Rhizoctonia solani AG-1 IA in Iran
Global diversity and distribution of three necrotrophic effectors in Phaeosphaeria nodorum and related species
Field-based experimental evolution of three cereal pathogens using a mark–release–recapture strategy
DNA fingerprinting of pearls to determine their origins
Coevolution and life cycle specialization of plant cell wall degrading enzymes in a hemibiotrophic pathogen
Association between virulence and triazole tolerance in the phytopathogenic fungus Mycosphaerella graminicola

2013: author

Breakage-fusion-bridge cycles and large insertions contribute to the rapid evolution of accessory chromosomes in a fungal pathogen


The accessory genome as a cradle for adaptive evolution in pathogens
Quantitative variation in effector activity of ToxA isoforms from Stagonospora nodorum and Pyrenophora tritici-repentis
Population genetic evidence that basidiospores play an important role in the disease cycle of rice-infecting populations of Rhizoctonia solani AG-1 IA in Iran
Phylogenetic and population genetic analyses of Phaeosphaeria nodorum and its close relatives indicate cryptic species and an origin in the fertile crescent
Local adaptation and evolutionary potential along a temperature gradient in the fungal pathogen Rhynchosporium commune
Intron gains and losses in the evolution of Fusarium and Cryptococcus fungi
Frequency of mutations associated with fungicide resistance and population structure of Mycosphaerella graminicola in Tunisia
Comparative pathogenomics reveals horizontally acquired novel virulence genes in fungi infecting cereal hosts
Zymoseptoria ardabiliae and Z. pseudotritici, two progenitor species of the septoria tritici leaf blotch fungus Z. tritici (synonym: Mycosphaerella graminicola)


Two new species of Rhynchosporium
Thermal adaptation in the fungal pathogen Mycosphaerella graminicola
The making of a new pathogen: Insights from comparative population genomics of the domesticated wheat pathoen Mycosphaerella graminicola and its wild sister species
No biogeographical pattern for a root-associated fungal species complex
Invasion of Rhynchosporium commune onto wild barley in the Middle East
Evolutionary history of the mitochondrial genome in Mycosphaerella populations infecting bread wheat, durum wheat and wild grasses
Evidence for extensive recent intron transposition in closely related fungi
Electrophoretic karyotypes of Rhynchosporium commune, R. secalis and R. agropyri
Effect of hosts on competition among clones and evidence of differential selection between pathogenic and saprophytic phases in experimental populations of the wheat pathogen Phaeosphaeria nodorum


Whole-genome and chromosome evolution associated with host adaptation and speciation of the wheat pathogen Mycosphaerella graminicola
Sexual recombinants make a significant contribution to epidemics caused by the wheat pathogen Phaeosphaeria nodorum
How can we achieve durable disease resistance in agricultural ecosystems?
Heritability under benign and stressful conditions in the plant pathogenic fungus Mycosphaerella graminicola
Evolution of linked avirulence effectors in Leptoshaeria maculans is affected by genomic environment and exposure to resistance genes in host plants


SnTox3 acts in effector triggered susceptibility to induce disease on wheat carrying the Snn3 gene
Sequence conservation in the mitochondrial cytochrome b gene and lack of G143A Qol resistance allele in a global sample of Rhynchosporium secalis
Qol resistance emerged independently at least 4 times in European populations of Mycosphaerella graminicola
Population genetics of fungal and Oomycete effectors involved in gene-for-gene interactions
Phylogeographical analyses reveal global migration patterns of the barley scald pathogen Rhynchosporium secalis
Molecular evidence for recent founder populations and human-mediated migration in the barley scald pathogen Rhynchosporium secalis
Genetic structure of populations of the rice-infecting pathogen Rhizoctonia solani AG-1 IA from China


The origins of plant pathogens in agro-ecosystems
Rapid speciation following recent host shifts in the plant pathogenic fungus Rhynchosporium
Intraspecific comparison and annotation of two complete mitochondrial genome sequences from the plant pathogenic fungus Mycosphaerella graminicola
Genetic structure of populations of Rhizoctonia solani anastomosis group-1 IA from soybean in Brazil
Evolution of the CYP51 gene in Mycosphaerella graminicola: evidence for intragenic recombination and selective replacement


The origin and colonization history of the barley scald pathogen Rhynchosporium secalis
Significant difference in pathogenicity between MAT1-1 and MAT1-2 isolates in the wheat pathogen Mycosphaerella graminicola
Sexual reproduction facilitates the adaptation of parasites to antagonistic host environments: Evidence from empirical study in the wheat-Mycosphaerella graminicola system
Origin and domestication of the fungal wheat pathogen Mycosphaerella graminicola via sympatric speciation
Geographic variation and positive diversifying selection in the host specific toxin SnToxA
Dothideomycete-Plant interactions illuminated by genome sequencing and EST analysis of the wheat pathogen Stagonospora nodorum
Concordant evolution of mitochondrial and nuclear genomes in the wheat pathogen Phaeosphaeria nodorum


The frequencies and spatial distribution of mating types in Stagonospora nodorum are consistent with recurring sexual reproduction.
Selection for increased cyproconazole tolerance in Mycosphaerella graminicola through local adaptation and in response to host resistance
Global migration patterns in the fungal wheat pathogen Phaeosphaeria nodorum
Global hierarchical gene diversity analysis suggests the Fertile Crescent is not the center of origin of the barley scald pathogen Rhynchosporium secalis
Genetic structure of Mycosphaerella graminicola populations from Iran, Argentina and Australia
Emergence of a new disease as a result of interspecific virulence gene transfer
Differential selection on Rhynchosporium secalis during parasitic and saprophytic phases in the barley disease cycle


Variation for neutral markers is correlated with variation for quantitative traits in the plant pathogenic fungus Mycosphaerella graminicola
Population structure of the rice sheath blight pathogen Rhizoctonia solani AG-1 IA from India
Migration patterns among global populations of the pathogenic fungus Mycosphaerella graminicola
Isolation and characterization of EST-derived microsatellite loci from the fungal wheat pathogen Phaeosphaeria nodorum


Phylogenetic analysis of globally distributed Mycosphaerella graminicola populations based on three DNA sequence loci
Molecular population genetic analysis differentiates two virulence mechanisms of the fungal avirulence gene NIP1
Genetic structure of Iranian Pyricularia grisea populations based on rep-PCR fingerprinting
Evidence for subdivision of the root-endophyte Phialocephala fortinii into cryptic species and recombination within species
Evidence for natural selection in the mitochondrial genome of Mycosphaerella graminicola


The global genetic structure of the wheat pathogen Mycosphaerella graminicola is characterized by high nuclear diversity, low mitochondrial diversity, regular recombination, and gene flow
Further evidence for sexual reproduction in Rhynchosporium secalis based on distribution and frequency of mating-type alleles
An analysis of the durability of resistance to plant viruses


The population genetics of plant pathogens and breeding strategies for durable resistance
Population structure of Mycosphaerella graminicola: from lesions to continents
Pathogen population genetics, evolutionary potential, and durable resistance
Local adaptation and effect of host genotype on the rate of pathogen evolution: an experimental test in a plant pathosystem
Intra- and intersporal diversity of ITS rDNA sequences in Glomus intraradices assessed by cloning and sequencing, and by SSCP analysis
Frequency of sexual reproduction by Mycosphaerella graminicola on partially resistant wheat cultivars
Distribution of mating type alleles in the wheat pathogen Mycosphaerella graminicola over spatial scales from lesions to continents


Using restriction fragment length polymorphisms to assess temporal variation and estimate the number of ascospores that initiate epidemics in field populations of Mycosphaerella graminicola


The genetic structure of field populations of Rhynchosporium secalis from three continents suggests moderate gene flow and regular recombination
Estimation of rates of recombination and migration in populations of plant pathogens - A reply


High levels of gene flow and heterozygote excess characterize Rhizoctonia solani AG-1 IA (Thanatephorus cucumeris) from Texas
Genetic structure of Rhynchosporium secalis in Australia


Measuring immigration and sexual reproduction in field populations of Mycosphaerella graminicola
Genetic structure and temporal dynamics of a Colletotrichum graminicola population in a sorghum disease nursery


The population genetics of fungi: tools and techniques
High genetic similarity among populations of Phaeosphaeria nodorum across wheat cultivars and regions in Switzerland
Gene flow and sexual reproduction in the wheat glume blotch pathogen Phaeosphaeria nodorum (anamorph Stagonospora nodorum)


The role of selection on the genetic structure of pathogen populations: Evidence from field experiments with Mycosphaerella graminicola on wheat
Sexual reproduction plays a major role in the genetic structure of populations of the fungus Mycosphaerella graminicola


Genetic variability in nuclear DNA in field populations of Stagonospora nodorum
Genetic stability in a population of a plant-pathogenic fungus over time


Population genetics of plant pathogenic fungi
Gene flow in plant pathosystems


DNA fingerprinting of the plant pathogenic fungus Mycosphaerella graminicola (anamorph Septoria tritici)
Chromosome length polymorphisms in a Septoria tritici population


Restriction fragment length polymorphisms in Septoria tritici occur at a high frequency
DNA restriction fragment length polymorphisms among Mycosphaerella graminicola (anamorph Septoria tritici) isolates collected from a single wheat field


The population biology of host pathogen interactions
Genetic variability for pathogenicity, isozyme, ribosomal DNA and colony color variants in populations of Rhynchosporium secalis
Coevolution of host and pathogen populations in the Hordeum vulgare - Rhynchosporium cecalis Pathosystem


Responses of 2-component, 3-component, and 4-component barley mixtures to a variable pathogen population
Bruce McDonald

ETH Zürich
Prof. Dr. Bruce McDonald
Institut f. Integrative Biologie
LFW B 16
Universitätstrasse 2
8092 Zuerich

Phone: +41 44 632 38 47
Fax: +41 44 632 15 72


Bruce McDonald was appointed Full Professor for Plant Pathology at the ETH on September 16, 1998.

Born in 1960, Bruce obtained a BSc degree in Plant Science from University of California at Riverside in 1982. He obtained his PhD degree in Genetics from University of California at Davis in 1987. He became an Assistant Professor in the Department of Plant Pathology at Texas A&M University in 1988, where he established an innovative research program oriented around understanding the population genetics and evolutionary biology of fungal plant pathogens. He spent sabbatical periods at CSIRO Plant Industry (Canberra, Australia) and University of California, San Diego.

His research lies at the intersection of the fields of plant pathology, population genetics, evolutionary biology, plant breeding and mycology, with a focus on major fungal pathogens of wheat, barley and rice. Bruce has published more than 110 peer-reviewed papers and presented more than 120 invited lectures at more than 50 universities and research institutes in more than 20 countries. He has reviewed hundreds of papers for the leading journals in plant pathology, genetics, evolutionary biology and mycology. The American Phytopathological Society recognized his fundamental contributions to plant pathology by awarding him the Ruth Allen Award in 1999 and elected him a Fellow in 2005. He was elected a Fellow of the American Association for the Advancement of Science (AAAS) in 2013.

Bruce joined the Institute of Plant Sciences (IPW) in November 1998 and served one term as Head of the IPW. In 2005 he joined the new Institute of Integrative Biology (IBZ) as one of its founding members and served as its Head in 2012. He served as Dean of the Department of Agricultural and Food Sciences from 2008-2010 and helped to launch the World Food System Center in 2011. Bruce also is a founding member and Director of the ETH Genetic Diversity Center. He served on the ETH Research Commission for five years. He participates in the Life Science Zurich graduate school in the Plant Science and Microbiology and Immunology programs. He served on the Editorial Boards of Phytopathology, the European Journal of Plant Pathology and PLoS Pathogens and has served on numerous national and international grant and evaluation panels.


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